Target

ATP1A4

Sodium/potassium-transporting ATPase subunit alpha-4

As of the edition of 20 October 2026, ATP1A4 (sodium/potassium-transporting ATPase subunit alpha-4, UniProt Q13733) has 5 drugs tested at it and 10 companies on the list, 0 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q13733
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
1
Disease areas
Heart and blood vessels; Cancer; Nutrition and metabolism; Hormones; Skin and connective tissue; Digestive system; Immune system; Infections
Registered trials of its drugs
197

Drugs at this target

StatusCount
Marketed4
Active1
Total5
DrugStatusFurthest phaseUS protection
DigoxinMarketedPhase 4none listed
IstaroximeActivePhase 3none listed
AcetyldigitoxinMarketedNo phase statednone listed
DeslanosideMarketedNo phase statednone listed
DigitoxinMarketedNo phase statednone listed

5 of 5 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Engaged6
Undetermined4
Total on the list10