Target

CALCB

Calcitonin gene-related peptide 2

As of the edition of 20 October 2026, CALCB (calcitonin gene-related peptide 2, UniProt P10092) has 3 drugs tested at it and 6 companies on the list, 0 on route A and 4 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P10092
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
Secreted
Disease areas
Nervous system; Mental health; Bones, joints and muscles; Ear, nose and throat; Mouth and teeth; Pregnancy and women's health; Urinary and reproductive; Cancer
Registered trials of its drugs
97

Drugs at this target

StatusCount
Marketed3
Total3
DrugStatusFurthest phaseUS protection
FremanezumabMarketedPhase 4Ends 2030
GalcanezumabMarketedPhase 4Ends 2030
EptinezumabMarketedPhase 4Ends 2032

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B4
Engaged1
Undetermined1
Total on the list6
Three companies on route A or B, with the route only
CompanyRoute
Eli LillyRoute B
OtsukaRoute B
LundbeckRoute B

The other 3 companies at CALCB

In the product

6 companies in all; 3 are not named here, and no score is.

See the 6 companies at CALCB, ranked, with the facts behind eachRequest access. Nothing is shown until you do.