Target

CCR5

C-C chemokine receptor type 5

As of the edition of 20 October 2026, CCR5 (C-C chemokine receptor type 5, UniProt P51681) has 13 drugs tested at it and 10 companies on the list, 8 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P51681
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
26
Disease areas
Infections; Immune system; Urinary and reproductive; Digestive system; Cancer; Lungs and airways; Skin and connective tissue; Nervous system
Registered trials of its drugs
203

Drugs at this target

StatusCount
Marketed1
Active1
Went quiet5
Stopped6
Total13
DrugStatusFurthest phaseUS protection
MaravirocMarketedPhase 4none listed
LeronlimabActivePhase 3none listed
CenicrivirocStoppedPhase 3none listed
VicrivirocWent quietPhase 3none listed
AZD5672Went quietPhase 2none listed
AplavirocStoppedPhase 3none listed
BMS-813160StoppedPhase 2none listed
GSK706769StoppedPhase 2none listed
PF-04634817StoppedPhase 2none listed
CCR5MAB004Went quietPhase 1none listed
HGS-1025StoppedPhase 1none listed
INCB-9471Went quietPhase 2none listed

12 of 13 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A8
Route B1
Engaged1
Total on the list10
Three companies on route A or B, with the route only
CompanyRoute
AbbVieRoute A
GSKRoute B
NovartisRoute A

The other 7 companies at CCR5

In the product

10 companies in all; 7 are not named here, and no score is.

See the 10 companies at CCR5, ranked, with the facts behind eachRequest access. Nothing is shown until you do.