Target

CD19

B-lymphocyte antigen CD19

As of the edition of 20 October 2026, CD19 (B-lymphocyte antigen CD19, UniProt P15391) has 22 drugs tested at it and 24 companies on the list, 4 on route A and 8 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P15391
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
4
Disease areas
Immune system; Cancer; Blood and lymph; Infections; Skin and connective tissue; Nervous system; Eye; Urinary and reproductive
Registered trials of its drugs
440

Drugs at this target

StatusCount
Marketed9
Active7
Went quiet2
Stopped3
Status not established1
Total22
DrugStatusFurthest phaseUS protection
BlinatumomabMarketedPhase 4Ends 2031
TafasitamabMarketedPhase 3Ends 2032
TisagenlecleucelMarketedPhase 3Ends 2029
Axicabtagene ciloleucelMarketedPhase 4Ends 2033
Loncastuximab tesirineMarketedPhase 3Ends 2033
Lisocabtagene maraleucelMarketedPhase 3Ends 2033
InebilizumabMarketedPhase 4Ends 2032
Brexucabtagene autoleucelMarketedPhase 2Ends 2032
BudoprutugActivePhase 2none listed
Obecabtagene autoleucelMarketedPhase 2Ends 2036
ObexelimabActivePhase 3none listed
YK012ActivePhase 2none listed

12 of 22 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A4
Route B8
Engaged11
Undetermined1
Total on the list24
Three companies on route A or B, with the route only
CompanyRoute
NovartisRoute B
Eli LillyRoute A
SanofiRoute A

The other 21 companies at CD19

In the product

24 companies in all; 21 are not named here, and no score is.

See the 24 companies at CD19, ranked, with the facts behind eachRequest access. Nothing is shown until you do.