Target

CD27

CD27 antigen

As of the edition of 20 October 2026, CD27 (CD27 antigen, UniProt P26842) has 3 drugs tested at it and 2 companies on the list, 0 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P26842
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
At a membrane
Solved structures
5
Disease areas
Cancer; Lungs and airways; Skin and connective tissue; Blood and lymph; Immune system; Urinary and reproductive; Digestive system; Hormones
Registered trials of its drugs
16

Drugs at this target

StatusCount
Active1
Stopped1
Status not established1
Total3
DrugStatusFurthest phaseUS protection
VarlilumabStoppedPhase 2none listed
BoserolimabActivePhase 2none listed
CDX-527Status not establishedPhase 1none listed

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Engaged1
Undetermined1
Total on the list2