Target

CD70

CD70 antigen

As of the edition of 20 October 2026, CD70 (CD70 antigen, UniProt P32970) has 4 drugs tested at it and 6 companies on the list, 3 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P32970
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
At a membrane
Solved structures
1
Disease areas
Cancer; Blood and lymph; Pregnancy and women's health; Urinary and reproductive; Immune system
Registered trials of its drugs
13

Drugs at this target

StatusCount
Active1
Went quiet1
Stopped2
Total4
DrugStatusFurthest phaseUS protection
CusatuzumabActivePhase 2none listed
MDX-1411StoppedPhase 1none listed
Vorsetuzumab mafodotinStoppedPhase 1none listed
AMG 172Went quietPhase 1none listed

4 of 4 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A3
Engaged2
Undetermined1
Total on the list6
Three companies on route A or B, with the route only
CompanyRoute
PfizerRoute A
Bristol Myers SquibbRoute A
AmgenRoute A

The other 3 companies at CD70

In the product

6 companies in all; 3 are not named here, and no score is.

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