CETP
Cholesteryl ester transfer protein
As of the edition of 20 October 2026, CETP (cholesteryl ester transfer protein, UniProt P11597) has 7 drugs tested at it and 13 companies on the list, 6 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P11597
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- Secreted
- Solved structures
- 3
- Disease areas
- Nutrition and metabolism; Heart and blood vessels; Inherited and neonatal; Digestive system; Hormones; Mental health; Nervous system; Pregnancy and women's health
- Registered trials of its drugs
- 109
Drugs at this target
| Status | Count |
|---|---|
| Active | 2 |
| Went quiet | 3 |
| Stopped | 2 |
| Total | 7 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Evacetrapib | Stopped | Phase 3 | none listed |
| Obicetrapib | Active | Phase 3 | none listed |
| Anacetrapib | Went quiet | Phase 3 | none listed |
| Dalcetrapib | Active | Phase 3 | none listed |
| Torcetrapib | Stopped | Phase 3 | none listed |
| Rocacetrapib | Went quiet | Phase 2 | none listed |
| K-312 | Went quiet | Phase 1 | none listed |
7 of 7 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 6 |
| Engaged | 7 |
| Total on the list | 13 |
| Company | Route |
|---|---|
| Merck & Co. | Route A |
| Pfizer | Route A |
| Roche | Route A |
The other 10 companies at CETP
In the product13 companies in all; 10 are not named here, and no score is.
See the 13 companies at CETP, ranked, with the facts behind eachRequest access. Nothing is shown until you do.