Target

CHRNA1

Acetylcholine receptor subunit alpha

As of the edition of 20 October 2026, CHRNA1 (acetylcholine receptor subunit alpha, UniProt P02708) has 14 drugs tested at it and 10 companies on the list, 0 on route A and 2 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P02708
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
27
Disease areas
Nervous system; Lungs and airways; Digestive system; Urinary and reproductive; Pregnancy and women's health; Heart and blood vessels; Cancer; Mental health
Registered trials of its drugs
218

Drugs at this target

StatusCount
Marketed13
Withdrawn from market1
Total14
DrugStatusFurthest phaseUS protection
RocuroniumMarketedPhase 4none listed
CisatracuriumMarketedPhase 4none listed
SuxamethoniumMarketedPhase 4none listed
AtracuriumMarketedPhase 4none listed
VecuroniumMarketedPhase 4none listed
MivacuriumMarketedPhase 4none listed
PipecuroniumMarketedPhase 4none listed
TubocurarineMarketedNo phase statednone listed
DecamethoniumMarketedNo phase statednone listed
DoxacuriumMarketedNo phase statednone listed
GallamineMarketedNo phase statednone listed
MetocurineMarketedNo phase statednone listed

12 of 14 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B2
Engaged2
Undetermined6
Total on the list10
Three companies on route A or B, with the route only
CompanyRoute
GSKRoute B
AbbVieRoute B

The other 8 companies at CHRNA1

In the product

10 companies in all; 8 are not named here, and no score is.

See the 10 companies at CHRNA1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.