CPS1
Carbamoyl-phosphate synthase [ammonia], mitochondrial
As of the edition of 20 October 2026, CPS1 (carbamoyl-phosphate synthase [ammonia], mitochondrial, UniProt P31327) has 1 drug tested at it and 2 companies on the list, 0 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P31327
- How well studied
- Drug target: an approved drug acts on it
- Where it sits in the cell
- In more than one place
- Solved structures
- 14
- Disease areas
- Inherited and neonatal; Nutrition and metabolism; Nervous system
- Registered trials of its drugs
- 8
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 1 |
| Total | 1 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Carglumic acid | Marketed | Phase 3 | Ends 2028 |
1 of 1 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Engaged | 2 |
| Total on the list | 2 |