Target

TFRC

Transferrin receptor protein 1

As of the edition of 20 October 2026, TFRC (transferrin receptor protein 1, UniProt P02786) has 4 drugs tested at it and 3 companies on the list, 0 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P02786
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
24
Disease areas
Inherited and neonatal; Nervous system; Nutrition and metabolism; Skin and connective tissue; Bones, joints and muscles; Blood and lymph; Cancer; Immune system
Registered trials of its drugs
12

Drugs at this target

StatusCount
Marketed1
Active1
Went quiet1
Status not established1
Total4
DrugStatusFurthest phaseUS protection
Pabinafusp alfaMarketedPhase 3none listed
AOC 1044ActivePhase 3none listed
A27.15Went quietPhase 1none listed
CX-2029Status not establishedPhase 2none listed

4 of 4 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B1
Engaged1
Undetermined1
Total on the list3
Three companies on route A or B, with the route only
CompanyRoute
JCR PharmaceuticalsRoute B

The other 2 companies at TFRC

In the product

3 companies in all; 2 are not named here, and no score is.

See the 3 companies at TFRC, ranked, with the facts behind eachRequest access. Nothing is shown until you do.