Target

CX3CL1

Fractalkine

As of the edition of 20 October 2026, CX3CL1 (fractalkine, UniProt P78423) has 1 drug tested at it and 2 companies on the list, 2 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P78423
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
In more than one place
Solved structures
15
Disease areas
Digestive system; Bones, joints and muscles; Immune system; Skin and connective tissue
Registered trials of its drugs
9

Drugs at this target

StatusCount
Stopped1
Total1
DrugStatusFurthest phaseUS protection
QuetmolimabStoppedPhase 2none listed

1 of 1 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Total on the list2
Three companies on route A or B, with the route only
CompanyRoute
EA PharmaRoute A
EisaiRoute A

The other 0 companies at CX3CL1

In the product

2 companies in all; 0 are not named here, and no score is.

See the 2 companies at CX3CL1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.