CXCL8
Interleukin-8
As of the edition of 20 October 2026, CXCL8 (interleukin-8, UniProt P10145) has 2 drugs tested at it and 2 companies on the list, 1 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P10145
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- Secreted
- Solved structures
- 22
- Disease areas
- Cancer; Digestive system; Lungs and airways; Blood and lymph; Infections; Skin and connective tissue; Hormones; Urinary and reproductive
- Registered trials of its drugs
- 12
Drugs at this target
| Status | Count |
|---|---|
| Went quiet | 1 |
| Stopped | 1 |
| Total | 2 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Adakitug | Stopped | Phase 2 | none listed |
| ABX-IL8 | Went quiet | Phase 2 | none listed |
2 of 2 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 1 |
| Engaged | 1 |
| Total on the list | 2 |
| Company | Route |
|---|---|
| Abgenix | Route A |
The other 1 company at CXCL8
In the product2 companies in all; 1 is not named here, and no score is.
See the 2 companies at CXCL8, ranked, with the facts behind eachRequest access. Nothing is shown until you do.