Target

DDC

Aromatic-L-amino-acid decarboxylase

As of the edition of 20 October 2026, DDC (aromatic-L-amino-acid decarboxylase, UniProt P20711) has 6 drugs tested at it and 10 companies on the list, 3 on route A and 3 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P20711
How well studied
Drug target: an approved drug acts on it
Solved structures
8
Disease areas
Nervous system; Mental health; Eye; Heart and blood vessels; Inherited and neonatal; Chemically induced; Immune system; Injuries
Registered trials of its drugs
134

Drugs at this target

StatusCount
Marketed3
Went quiet3
Total6
DrugStatusFurthest phaseUS protection
Carbidopa anhydrousMarketedPhase 4none listed
BenserazideMarketedPhase 4none listed
IPX054Went quietPhase 2none listed
ND0612Went quietPhase 3none listed
WD-1603Went quietPhase 1none listed
FoscarbidopaMarketedNo phase statedEnds 2035

6 of 6 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A3
Route B3
Engaged1
Undetermined3
Total on the list10
Three companies on route A or B, with the route only
CompanyRoute
RocheRoute B
NovartisRoute B
NeuroDermRoute A

The other 7 companies at DDC

In the product

10 companies in all; 7 are not named here, and no score is.

See the 10 companies at DDC, ranked, with the facts behind eachRequest access. Nothing is shown until you do.