FFAR1
Free fatty acid receptor 1
As of the edition of 20 October 2026, FFAR1 (free fatty acid receptor 1, UniProt O14842) has 10 drugs tested at it and 9 companies on the list, 6 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- O14842
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- At a membrane
- Solved structures
- 9
- Disease areas
- Nutrition and metabolism; Hormones; Inherited and neonatal; Lungs and airways; Digestive system; Eye; Heart and blood vessels; Nervous system
- Registered trials of its drugs
- 37
Drugs at this target
| Status | Count |
|---|---|
| Active | 2 |
| Went quiet | 5 |
| Stopped | 2 |
| Status not established | 1 |
| Total | 10 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Fasiglifam | Stopped | Phase 3 | none listed |
| Setogepram | Stopped | Phase 3 | none listed |
| CPL207280 | Active | Phase 2 | none listed |
| HD-6277 | Active | Phase 2 | none listed |
| LY2922470 | Went quiet | Phase 1 | none listed |
| JTT-851 | Went quiet | Phase 2 | none listed |
| K-757 | Status not established | Phase 1 | none listed |
| LY2881835 | Went quiet | Phase 1 | none listed |
| MK-8666 | Went quiet | Phase 1 | none listed |
| P11187 | Went quiet | Phase 1 | none listed |
10 of 10 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 6 |
| Engaged | 2 |
| Undetermined | 1 |
| Total on the list | 9 |
| Company | Route |
|---|---|
| Takeda | Route A |
| Liminal BioSciences | Route A |
| Eli Lilly | Route A |
The other 6 companies at FFAR1
In the product9 companies in all; 6 are not named here, and no score is.
See the 9 companies at FFAR1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.