Target

GIPR

Gastric inhibitory polypeptide receptor

As of the edition of 20 October 2026, GIPR (gastric inhibitory polypeptide receptor, UniProt P48546) has 5 drugs tested at it and 4 companies on the list, 0 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P48546
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
14
Disease areas
Nutrition and metabolism; Hormones; Urinary and reproductive; Heart and blood vessels; Cancer; Pregnancy and women's health; Digestive system; Immune system
Registered trials of its drugs
237

Drugs at this target

StatusCount
Marketed1
Active3
Status not established1
Total5
DrugStatusFurthest phaseUS protection
TirzepatideMarketedPhase 4Ends 2039
RetatrutideActivePhase 3none listed
PF-07976016ActivePhase 2none listed
LY3537021ActivePhase 2none listed
KP405Status not establishedPhase 1none listed

5 of 5 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B1
Engaged2
Undetermined1
Total on the list4
Three companies on route A or B, with the route only
CompanyRoute
Eli LillyRoute B

The other 3 companies at GIPR

In the product

4 companies in all; 3 are not named here, and no score is.

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