Target

GSK3A

Glycogen synthase kinase-3 alpha

As of the edition of 20 October 2026, GSK3A (glycogen synthase kinase-3 alpha, UniProt P49840) has 3 drugs tested at it and 10 companies on the list, 1 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P49840
How well studied
Drug target: an approved drug acts on it
Solved structures
2
Disease areas
Nervous system; Mental health; Cancer; Inherited and neonatal; Injuries; Blood and lymph; Nutrition and metabolism; Chemically induced
Registered trials of its drugs
68

Drugs at this target

StatusCount
Marketed2
Stopped1
Total3
DrugStatusFurthest phaseUS protection
Lithium carbonateMarketedPhase 4none listed
LY-2090314StoppedPhase 2none listed
Lithium citrate anhydrousMarketedNo phase statednone listed

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Route B1
Engaged8
Total on the list10
Three companies on route A or B, with the route only
CompanyRoute
Eli LillyRoute A
PfizerRoute B

The other 8 companies at GSK3A

In the product

10 companies in all; 8 are not named here, and no score is.

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