Target

GSK3B

Glycogen synthase kinase-3 beta

As of the edition of 20 October 2026, GSK3B (glycogen synthase kinase-3 beta, UniProt P49841) has 5 drugs tested at it and 13 companies on the list, 1 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P49841
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
123
Disease areas
Nervous system; Mental health; Cancer; Inherited and neonatal; Injuries; Blood and lymph; Bones, joints and muscles; Nutrition and metabolism
Registered trials of its drugs
87

Drugs at this target

StatusCount
Marketed2
Active2
Stopped1
Total5
DrugStatusFurthest phaseUS protection
Lithium carbonateMarketedPhase 4none listed
ElraglusibActivePhase 2none listed
TideglusibActivePhase 3none listed
LY-2090314StoppedPhase 2none listed
Lithium citrate anhydrousMarketedNo phase statednone listed

5 of 5 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Route B1
Engaged11
Total on the list13
Three companies on route A or B, with the route only
CompanyRoute
Eli LillyRoute A
PfizerRoute B

The other 11 companies at GSK3B

In the product

13 companies in all; 11 are not named here, and no score is.

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