Target

GSR

Glutathione reductase, mitochondrial

As of the edition of 20 October 2026, GSR (glutathione reductase, mitochondrial, UniProt P00390) has 2 drugs tested at it and 6 companies on the list, 0 on route A and 2 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P00390
How well studied
Drug target: an approved drug acts on it
Solved structures
27
Disease areas
Cancer; Immune system; Blood and lymph; Nervous system; Heart and blood vessels; Infections; Skin and connective tissue; Urinary and reproductive
Registered trials of its drugs
201

Drugs at this target

StatusCount
Marketed2
Total2
DrugStatusFurthest phaseUS protection
CarmustineMarketedPhase 3none listed
OxiglutationeMarketedPhase 4none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B2
Engaged4
Total on the list6
Three companies on route A or B, with the route only
CompanyRoute
AlconRoute B
NobelpharmaRoute B

The other 4 companies at GSR

In the product

6 companies in all; 4 are not named here, and no score is.

See the 6 companies at GSR, ranked, with the facts behind eachRequest access. Nothing is shown until you do.