HCAR2
Hydroxycarboxylic acid receptor 2
As of the edition of 20 October 2026, HCAR2 (hydroxycarboxylic acid receptor 2, UniProt Q8TDS4) has 6 drugs tested at it and 5 companies on the list, 2 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- Q8TDS4
- How well studied
- Drug target: an approved drug acts on it
- Where it sits in the cell
- At a membrane
- Solved structures
- 40
- Disease areas
- Nutrition and metabolism; Heart and blood vessels; Hormones; Nervous system; Inherited and neonatal; Immune system; Urinary and reproductive; Cancer
- Registered trials of its drugs
- 139
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 2 |
| Went quiet | 3 |
| Stopped | 1 |
| Total | 6 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Niacin | Marketed | Phase 4 | none listed |
| Acipimox | Marketed | Phase 3 | none listed |
| GSK256073 | Went quiet | Phase 2 | none listed |
| MK0354 | Stopped | Phase 2 | none listed |
| MK1903 | Went quiet | Phase 2 | none listed |
| SCH-900271 | Went quiet | Phase 2 | none listed |
6 of 6 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 2 |
| Engaged | 3 |
| Total on the list | 5 |
| Company | Route |
|---|---|
| Merck & Co. | Route A |
| GSK | Route A |
The other 3 companies at HCAR2
In the product5 companies in all; 3 are not named here, and no score is.
See the 5 companies at HCAR2, ranked, with the facts behind eachRequest access. Nothing is shown until you do.