HTT
Huntingtin
As of the edition of 20 October 2026, HTT (huntingtin, UniProt P42858) has 1 drug tested at it and 2 companies on the list, 0 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P42858
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- Inside the cell
- Solved structures
- 30
- Disease areas
- Nervous system; Inherited and neonatal; Mental health
- Registered trials of its drugs
- 6
Drugs at this target
| Status | Count |
|---|---|
| Active | 1 |
| Total | 1 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Tominersen | Active | Phase 3 | none listed |
1 of 1 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Engaged | 2 |
| Total on the list | 2 |