Target

ITGA5

Integrin alpha-5

As of the edition of 20 October 2026, ITGA5 (integrin alpha-5, UniProt P08648) has 3 drugs tested at it and 5 companies on the list, 5 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P08648
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
In more than one place
Solved structures
16
Disease areas
Cancer; Pregnancy and women's health; Urinary and reproductive; Hormones; Lungs and airways; Digestive system; Skin and connective tissue; Eye
Registered trials of its drugs
13

Drugs at this target

StatusCount
Went quiet2
Stopped1
Total3
DrugStatusFurthest phaseUS protection
VolociximabWent quietPhase 2none listed
ATN-161Went quietPhase 2none listed
PF-04605412StoppedPhase 1none listed

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A5
Total on the list5
Three companies on route A or B, with the route only
CompanyRoute
PfizerRoute A
AbbVieRoute A
AstellasRoute A

The other 2 companies at ITGA5

In the product

5 companies in all; 2 are not named here, and no score is.

See the 5 companies at ITGA5, ranked, with the facts behind eachRequest access. Nothing is shown until you do.