LYN
Tyrosine-protein kinase Lyn
As of the edition of 20 October 2026, LYN (tyrosine-protein kinase Lyn, UniProt P07948) has 9 drugs tested at it and 10 companies on the list, 6 on route A and 1 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P07948
- How well studied
- Drug target: an approved drug acts on it
- Where it sits in the cell
- In more than one place
- Solved structures
- 6
- Disease areas
- Cancer; Blood and lymph; Immune system; Digestive system; Skin and connective tissue; Lungs and airways; Nervous system; Hormones
- Registered trials of its drugs
- 337
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 1 |
| Active | 1 |
| Went quiet | 4 |
| Stopped | 3 |
| Total | 9 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Dasatinib anhydrous | Marketed | Phase 4 | Ended 2026 |
| DZD8586 | Active | Phase 3 | none listed |
| ENMD-981693 | Went quiet | Phase 2 | none listed |
| Bafetinib | Went quiet | Phase 2 | none listed |
| Ilorasertib | Stopped | Phase 2 | none listed |
| TG100-801 | Stopped | Phase 2 | none listed |
| XL-228 | Stopped | Phase 1 | none listed |
| JNJ-26483327 | Went quiet | Phase 1 | none listed |
| Tolimidone | Went quiet | Phase 2 | none listed |
9 of 9 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 6 |
| Route B | 1 |
| Engaged | 3 |
| Total on the list | 10 |
| Company | Route |
|---|---|
| Johnson & Johnson | Route A |
| LadRx | Route A |
| Melior Pharmaceuticals | Route A |
The other 7 companies at LYN
In the product10 companies in all; 7 are not named here, and no score is.
See the 10 companies at LYN, ranked, with the facts behind eachRequest access. Nothing is shown until you do.