Target

NOD2

Nucleotide-binding oligomerization domain-containing protein 2

As of the edition of 20 October 2026, NOD2 (nucleotide-binding oligomerization domain-containing protein 2, UniProt Q9HC29) has 2 drugs tested at it and 4 companies on the list, 2 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q9HC29
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
In more than one place
Disease areas
Cancer; Digestive system; Infections; Immune system; Lungs and airways
Registered trials of its drugs
12

Drugs at this target

StatusCount
Marketed1
Stopped1
Total2
DrugStatusFurthest phaseUS protection
Mifamurtide acidMarketedPhase 2none listed
Inarigivir soproxilStoppedPhase 2none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Undetermined2
Total on the list4
Three companies on route A or B, with the route only
CompanyRoute
invoX PharmaRoute A
Gilead SciencesRoute A

The other 2 companies at NOD2

In the product

4 companies in all; 2 are not named here, and no score is.

See the 4 companies at NOD2, ranked, with the facts behind eachRequest access. Nothing is shown until you do.