NOX4
NADPH oxidase 4
As of the edition of 20 October 2026, NOX4 (NADPH oxidase 4, UniProt Q9NPH5) has 1 drug tested at it and 2 companies on the list, 0 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- Q9NPH5
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- In more than one place
- Disease areas
- Digestive system; Pregnancy and women's health; Urinary and reproductive; Cancer; Hormones; Inherited and neonatal; Lungs and airways; Nutrition and metabolism
- Registered trials of its drugs
- 8
Drugs at this target
| Status | Count |
|---|---|
| Active | 1 |
| Total | 1 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Setanaxib | Active | Phase 2 | none listed |
1 of 1 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Engaged | 1 |
| Undetermined | 1 |
| Total on the list | 2 |