Target

PGR

Progesterone receptor

As of the edition of 20 October 2026, PGR (progesterone receptor, UniProt P06401) has 36 drugs tested at it and 47 companies on the list, 2 on route A and 16 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P06401
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
Inside the cell
Solved structures
21
Disease areas
Urinary and reproductive; Pregnancy and women's health; Cancer; Hormones; Mental health; Skin and connective tissue; Nutrition and metabolism; Immune system
Registered trials of its drugs
1,200

Drugs at this target

StatusCount
Marketed26
Went quiet7
Stopped3
Total36
DrugStatusFurthest phaseUS protection
ProgesteroneMarketedPhase 4none listed
LevonorgestrelMarketedPhase 4none listed
MifepristoneMarketedPhase 4none listed
Medroxyprogesterone acetateMarketedPhase 4none listed
Megestrol acetateMarketedPhase 4none listed
DrospirenoneMarketedPhase 4none listed
Ulipristal acetateMarketedPhase 4none listed
DydrogesteroneMarketedPhase 4none listed
EtonogestrelMarketedPhase 4Ends 2029
Norethindrone acetateMarketedPhase 4none listed
DienogestMarketedPhase 4none listed
NorethindroneMarketedPhase 4none listed

12 of 36 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Route B16
Engaged18
Undetermined11
Total on the list47
Three companies on route A or B, with the route only
CompanyRoute
AbbVieRoute B
Eli LillyRoute B
LinepharmaRoute B

The other 44 companies at PGR

In the product

47 companies in all; 44 are not named here, and no score is.

See the 47 companies at PGR, ranked, with the facts behind eachRequest access. Nothing is shown until you do.