Probatebeta
Target

PIK3CG

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

As of the edition of 20 October 2026, PIK3CG (phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, UniProt P48736) has 31 drugs tested at it and 35 companies on the list, 22 on route A and 2 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P48736
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
107
Disease areas
Cancer; Blood and lymph; Skin and connective tissue; Immune system; Lungs and airways; Urinary and reproductive; Nervous system; Pregnancy and women's health
Registered trials of its drugs
342

Drugs at this target

StatusCount
Marketed2
Active4
Went quiet12
Stopped12
Status not established1
Total31
DrugStatusFurthest phaseUS protection
BuparlisibStoppedPhase 3none listed
DuvelisibMarketedPhase 3Ends 2032
DactolisibWent quietPhase 3none listed
GedatolisibMarketedPhase 3Ends 2031
SamotolisibStoppedPhase 2none listed
PictilisibWent quietPhase 2none listed
TaselisibStoppedPhase 3none listed
PaxalisibActivePhase 3none listed
PilaralisibWent quietPhase 2none listed
ApitolisibActivePhase 2none listed
TenalisibActivePhase 2none listed
VoxtalisibWent quietPhase 2none listed

12 of 31 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A22
Route B2
Engaged9
Undetermined2
Total on the list35
Three companies on route A or B, with the route only
CompanyRoute
NovartisRoute A
GSKRoute A
SanofiRoute A

The other 32 companies at PIK3CG

In the product

35 companies in all; 32 are not named here, and no score is.

See the 35 companies at PIK3CG, ranked, with the facts behind eachRequest access. Nothing is shown until you do.

More drugs at PIK3CG

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