Target

PLA2G2A

Phospholipase A2, membrane associated

As of the edition of 20 October 2026, PLA2G2A (phospholipase A2, membrane associated, UniProt P14555) has 2 drugs tested at it and 2 companies on the list, 2 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P14555
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
17
Disease areas
Heart and blood vessels; Chemically induced; Injuries; Infections; Lungs and airways; Pregnancy and women's health; Urinary and reproductive
Registered trials of its drugs
8

Drugs at this target

StatusCount
Stopped2
Total2
DrugStatusFurthest phaseUS protection
Varespladib methylStoppedPhase 3none listed
VarespladibStoppedPhase 2none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Total on the list2
Three companies on route A or B, with the route only
CompanyRoute
OphirexRoute A
Anthera PharmaceuticalsRoute A

The other 0 companies at PLA2G2A

In the product

2 companies in all; 0 are not named here, and no score is.

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