Target

PLAT

Tissue-type plasminogen activator

As of the edition of 20 October 2026, PLAT (tissue-type plasminogen activator, UniProt P00750) has 1 drug tested at it and 4 companies on the list, 0 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P00750
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
Secreted
Solved structures
11
Disease areas
Bones, joints and muscles; Heart and blood vessels; Inherited and neonatal; Blood and lymph; Cancer; Infections; Nervous system
Registered trials of its drugs
16

Drugs at this target

StatusCount
Marketed1
Total1
DrugStatusFurthest phaseUS protection
Aminocaproic acidMarketedPhase 4none listed

1 of 1 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Undetermined4
Total on the list4