Target

PRKCA

Protein kinase C alpha type

As of the edition of 20 October 2026, PRKCA (protein kinase C alpha type, UniProt P17252) has 2 drugs tested at it and 2 companies on the list, 2 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P17252
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
6
Disease areas
Cancer; Lungs and airways; Skin and connective tissue
Registered trials of its drugs
5

Drugs at this target

StatusCount
Went quiet2
Total2
DrugStatusFurthest phaseUS protection
Isis 3521Went quietPhase 3none listed
AprinocarsenWent quietPhase 3none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Total on the list2
Three companies on route A or B, with the route only
CompanyRoute
Eli LillyRoute A
Akcea TherapeuticsRoute A

The other 0 companies at PRKCA

In the product

2 companies in all; 0 are not named here, and no score is.

See the 2 companies at PRKCA, ranked, with the facts behind eachRequest access. Nothing is shown until you do.