Target

PTK2B

Protein-tyrosine kinase 2-beta

As of the edition of 20 October 2026, PTK2B (protein-tyrosine kinase 2-beta, UniProt Q14289) has 2 drugs tested at it and 2 companies on the list, 0 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q14289
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
26
Disease areas
Cancer; Hormones; Digestive system; Lungs and airways; Pregnancy and women's health; Urinary and reproductive; Blood and lymph; Heart and blood vessels
Registered trials of its drugs
41

Drugs at this target

StatusCount
Marketed1
Status not established1
Total2
DrugStatusFurthest phaseUS protection
DefactinibMarketedPhase 3none listed
ConteltinibStatus not establishedPhase 2none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Engaged1
Undetermined1
Total on the list2