Target

RYR1

Ryanodine receptor 1

As of the edition of 20 October 2026, RYR1 (ryanodine receptor 1, UniProt P21817) has 1 drug tested at it and 4 companies on the list, 0 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P21817
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
2
Disease areas
Nervous system; Heart and blood vessels; Injuries; Ear, nose and throat; Eye; Hormones; Immune system; Inherited and neonatal
Registered trials of its drugs
11

Drugs at this target

StatusCount
Marketed1
Total1
DrugStatusFurthest phaseUS protection
DantroleneMarketedPhase 3none listed

1 of 1 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B1
Undetermined3
Total on the list4
Three companies on route A or B, with the route only
CompanyRoute
NorgineRoute B

The other 3 companies at RYR1

In the product

4 companies in all; 3 are not named here, and no score is.

See the 4 companies at RYR1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.