Target

RYR2

Ryanodine receptor 2

As of the edition of 20 October 2026, RYR2 (ryanodine receptor 2, UniProt Q92736) has 2 drugs tested at it and 4 companies on the list, 2 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q92736
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
26
Disease areas
Heart and blood vessels; Pregnancy and women's health; Urinary and reproductive; Cancer; Nervous system; Skin and connective tissue; Hormones; Inherited and neonatal
Registered trials of its drugs
36

Drugs at this target

StatusCount
Marketed1
Stopped1
Total2
DrugStatusFurthest phaseUS protection
HydralazineMarketedPhase 4none listed
K201StoppedPhase 2none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Route B1
Undetermined1
Total on the list4
Three companies on route A or B, with the route only
CompanyRoute
SterimaxRoute B
Moberg PharmaRoute A
Sequel PharmaceuticalsRoute A

The other 1 company at RYR2

In the product

4 companies in all; 1 is not named here, and no score is.

See the 4 companies at RYR2, ranked, with the facts behind eachRequest access. Nothing is shown until you do.