Target

SLC12A1

Solute carrier family 12 member 1

As of the edition of 20 October 2026, SLC12A1 (solute carrier family 12 member 1, UniProt Q13621) has 6 drugs tested at it and 36 companies on the list, 1 on route A and 3 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q13621
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Disease areas
Heart and blood vessels; Urinary and reproductive; Pregnancy and women's health; Lungs and airways; Nutrition and metabolism; Inherited and neonatal; Cancer; Mental health
Registered trials of its drugs
234

Drugs at this target

StatusCount
Marketed5
Went quiet1
Total6
DrugStatusFurthest phaseUS protection
FurosemideMarketedPhase 4none listed
TorsemideMarketedPhase 4none listed
BumetanideMarketedPhase 4none listed
Ethacrynic acidMarketedPhase 2none listed
CLS006Went quietPhase 3none listed
PiretanideMarketedNo phase statednone listed

6 of 6 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Route B3
Engaged2
Undetermined30
Total on the list36
Three companies on route A or B, with the route only
CompanyRoute
Proveca PharmaRoute B
RocheRoute B
MaruhoRoute A

The other 33 companies at SLC12A1

In the product

36 companies in all; 33 are not named here, and no score is.

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