Target

SNAP25

Synaptosomal-associated protein 25

As of the edition of 20 October 2026, SNAP25 (synaptosomal-associated protein 25, UniProt P60880) has 10 drugs tested at it and 9 companies on the list, 0 on route A and 3 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P60880
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
14
Disease areas
Nervous system; Bones, joints and muscles; Urinary and reproductive; Pregnancy and women's health; Heart and blood vessels; Skin and connective tissue; Mouth and teeth; Injuries
Registered trials of its drugs
722

Drugs at this target

StatusCount
Marketed8
Active1
Status not established1
Total10
DrugStatusFurthest phaseUS protection
Botulinum toxin type aMarketedPhase 4none listed
OnabotulinumtoxinaMarketedPhase 4Ended 2026
IncobotulinumtoxinaMarketedPhase 4Ended 2022
AbobotulinumtoxinaMarketedPhase 4Ended 2023
Prabotulinumtoxin aMarketedPhase 4Ends 2031
DaxibotulinumtoxinaMarketedPhase 4Ends 2034
TrenibotulinumtoxineMarketedPhase 3none listed
LetibotulinumtoxinaMarketedPhase 3Ends 2036
RT001ActivePhase 3none listed
YY001Status not establishedPhase 2none listed

10 of 10 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B3
Engaged3
Undetermined3
Total on the list9
Three companies on route A or B, with the route only
CompanyRoute
HugelRoute B
Merz Pharma GmbH & Co. KGaARoute B
CrownRoute B

The other 6 companies at SNAP25

In the product

9 companies in all; 6 are not named here, and no score is.

See the 9 companies at SNAP25, ranked, with the facts behind eachRequest access. Nothing is shown until you do.