Target

SNCA

Alpha-synuclein

As of the edition of 20 October 2026, SNCA (alpha-synuclein, UniProt P37840) has 5 drugs tested at it and 7 companies on the list, 3 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P37840
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
253
Disease areas
Nervous system; Mental health
Registered trials of its drugs
21

Drugs at this target

StatusCount
Active2
Went quiet1
Stopped2
Total5
DrugStatusFurthest phaseUS protection
EmrusolminActivePhase 2none listed
PrasinezumabActivePhase 3none listed
MinzasolminStoppedPhase 2none listed
CinpanemabStoppedPhase 2none listed
NPT200-11Went quietPhase 1none listed

5 of 5 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A3
Engaged4
Total on the list7
Three companies on route A or B, with the route only
CompanyRoute
Neuropore TherapiesRoute A
UCBRoute A
BiogenRoute A

The other 4 companies at SNCA

In the product

7 companies in all; 4 are not named here, and no score is.

See the 7 companies at SNCA, ranked, with the facts behind eachRequest access. Nothing is shown until you do.