Target

TLR3

Toll-like receptor 3

As of the edition of 20 October 2026, TLR3 (toll-like receptor 3, UniProt O15455) has 2 drugs tested at it and 3 companies on the list, 2 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
O15455
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
In more than one place
Solved structures
20
Disease areas
Cancer; Urinary and reproductive; Infections; Digestive system; Immune system; Eye; Hormones; Skin and connective tissue
Registered trials of its drugs
31

Drugs at this target

StatusCount
Stopped2
Total2
DrugStatusFurthest phaseUS protection
RintatolimodStoppedPhase 3none listed
BevasiranibStoppedPhase 3none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Engaged1
Total on the list3
Three companies on route A or B, with the route only
CompanyRoute
AIM ImmunoTechRoute A
OPKO HealthRoute A

The other 1 company at TLR3

In the product

3 companies in all; 1 is not named here, and no score is.

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