TNKS2
Poly [ADP-ribose] polymerase tankyrase-2
As of the edition of 20 October 2026, TNKS2 (poly [ADP-ribose] polymerase tankyrase-2, UniProt Q9H2K2) has 1 drug tested at it and 2 companies on the list, 0 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- Q9H2K2
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- In more than one place
- Solved structures
- 201
- Disease areas
- Cancer; Skin and connective tissue; Blood and lymph; Hormones; Immune system; Lungs and airways; Pregnancy and women's health; Urinary and reproductive
- Registered trials of its drugs
- 6
Drugs at this target
| Status | Count |
|---|---|
| Active | 1 |
| Total | 1 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| 2X-121 | Active | Phase 2 | none listed |
1 of 1 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Engaged | 2 |
| Total on the list | 2 |