Target

TRPV4

Transient receptor potential cation channel subfamily V member 4

As of the edition of 20 October 2026, TRPV4 (transient receptor potential cation channel subfamily V member 4, UniProt Q9HBA0) has 2 drugs tested at it and 2 companies on the list, 1 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q9HBA0
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
19
Disease areas
Heart and blood vessels; Lungs and airways; Eye
Registered trials of its drugs
5

Drugs at this target

StatusCount
Marketed1
Stopped1
Total2
DrugStatusFurthest phaseUS protection
GSK2798745StoppedPhase 2none listed
ButambenMarketedNo phase statednone listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Undetermined1
Total on the list2
Three companies on route A or B, with the route only
CompanyRoute
GSKRoute A

The other 1 company at TRPV4

In the product

2 companies in all; 1 is not named here, and no score is.

See the 2 companies at TRPV4, ranked, with the facts behind eachRequest access. Nothing is shown until you do.