TUBA1B
Tubulin alpha-1B chain
As of the edition of 20 October 2026, TUBA1B (tubulin alpha-1B chain, UniProt P68363) has 4 drugs tested at it and 6 companies on the list, 2 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P68363
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- Inside the cell
- Solved structures
- 40
- Disease areas
- Cancer; Skin and connective tissue; Digestive system; Pregnancy and women's health; Urinary and reproductive; Lungs and airways
- Registered trials of its drugs
- 37
Drugs at this target
| Status | Count |
|---|---|
| Active | 3 |
| Went quiet | 1 |
| Total | 4 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| RC48-ADC | Active | Phase 3 | none listed |
| HB1801 | Active | Phase 3 | none listed |
| SOR007 | Went quiet | Phase 2 | none listed |
| E7389-LF | Active | Phase 2 | none listed |
4 of 4 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 2 |
| Engaged | 4 |
| Total on the list | 6 |
The other 4 companies at TUBA1B
In the product6 companies in all; 4 are not named here, and no score is.
See the 6 companies at TUBA1B, ranked, with the facts behind eachRequest access. Nothing is shown until you do.