XDH
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase
As of the edition of 20 October 2026, XDH (xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase, UniProt P47989) has 6 drugs tested at it and 15 companies on the list, 1 on route A and 2 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P47989
- How well studied
- Drug target: an approved drug acts on it
- Where it sits in the cell
- In more than one place
- Solved structures
- 2
- Disease areas
- Nutrition and metabolism; Inherited and neonatal; Bones, joints and muscles; Heart and blood vessels; Cancer; Immune system; Blood and lymph; Urinary and reproductive
- Registered trials of its drugs
- 193
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 3 |
| Active | 1 |
| Went quiet | 1 |
| Withdrawn from market | 1 |
| Total | 6 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Allopurinol | Marketed | Phase 4 | none listed |
| Febuxostat | Marketed | Phase 4 | none listed |
| Tigulixostat | Active | Phase 3 | none listed |
| Oxypurinol | Went quiet | Phase 3 | none listed |
| Topiroxostat | Marketed | Phase 2 | none listed |
| Bendazac | Withdrawn from market | No phase stated | none listed |
6 of 6 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 1 |
| Route B | 2 |
| Engaged | 5 |
| Undetermined | 7 |
| Total on the list | 15 |
| Company | Route |
|---|---|
| Takeda | Route B |
| Teijin Pharma | Route B |
| Advanz Pharma | Route A |
The other 12 companies at XDH
In the product15 companies in all; 12 are not named here, and no score is.
See the 15 companies at XDH, ranked, with the facts behind eachRequest access. Nothing is shown until you do.