Company

Alnylam Pharmaceuticals

As of the edition of 20 October 2026, Alnylam Pharmaceuticals runs 21 drugs, 7 of them marketed; it is on route A at 1 target and on route B at 4 targets.

Sources: ClinicalTrials.gov, FDA Orange Book and Purple Book, other approval registers, company records.

Family history

The records place 2 company names in this family.

Drugs by status

StatusCount
Marketed7
Active12
Went quiet2
Total21

Marketed drugs and when their US protection ends

DrugUS protectionRoute B rows
Patisirannone listed0
LumasiranEnds 2038 (patent)3
Givosirannone listed1
Vutrisirannone listed0
Givosiran sodiumEnds 2034 (patent)1
Patisiran sodiumEnds 2035 (patent)0
Vutrisiran sodiumEnds 2036 (patent)0

A route B row is one company at one target.

Where it needs a new molecule

Route A at 1 target, route B at 4 targets.

Three of its 5 rows, by target and route
TargetRoute
ALAS1 5-aminolevulinate synthase, non-specific, mitochondrialRoute B
ASGR1 Asialoglycoprotein receptor 1Route B
HAO1 2-Hydroxyacid oxidase 1Route B

All 5 rows on route A or B

In the product

5 company-target rows on route A or B; 2 are not shown here, and no score is.

Where its trials are

  • Nutrition and metabolism: 27 trials led
  • Inherited and neonatal: 20 trials led
  • Heart and blood vessels: 15 trials led