Target

ASGR2

Asialoglycoprotein receptor 2

As of the edition of 20 October 2026, ASGR2 (asialoglycoprotein receptor 2, UniProt P07307) has 3 drugs tested at it and 2 companies on the list, 0 on route A and 2 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P07307
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
At a membrane
Solved structures
1
Disease areas
Pregnancy and women's health; Urinary and reproductive; Inherited and neonatal; Nutrition and metabolism; Heart and blood vessels
Registered trials of its drugs
15

Drugs at this target

StatusCount
Marketed3
Total3
DrugStatusFurthest phaseUS protection
LumasiranMarketedPhase 3Ends 2038
Nedosiran sodiumMarketedPhase 3Ends 2038
NedosiranMarketedPhase 2none listed

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B2
Total on the list2
Three companies on route A or B, with the route only
CompanyRoute
Alnylam PharmaceuticalsRoute B
Novo NordiskRoute B

The other 0 companies at ASGR2

In the product

2 companies in all; 0 are not named here, and no score is.

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