Drug

Apinocaltamide

As of the edition of 20 October 2026, Apinocaltamide is a small molecule: stopped in 2025; acts on CACNA1G, CACNA1H and CACNA1I.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2025
Kind
Small molecule
Registered trials
5, 1 stopped early
Disease areas
Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of Apinocaltamide.

Targets

GeneProteinUniProt
CACNA1GVoltage-dependent T-type calcium channel subunit alpha-1GO43497
CACNA1HVoltage-dependent T-type calcium channel subunit alpha-1HO95180
CACNA1IVoltage-dependent T-type calcium channel subunit alpha-1IQ9P0X4

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 23201
All trials5

Who ran its trials

CompanyRoleYears
Idorsia PharmaceuticalsLead sponsor of trials2017 to now
NeurocrineLead sponsor of trials2021 to now