Drug

Mibefradil

As of the edition of 20 October 2026, Mibefradil is a small molecule: withdrawn from the market in 1998; acts on CACNA1G, CACNA1H and CACNA1I.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Withdrawn from market, 1998
Kind
Small molecule
Withdrawn from market
1 January 1998 (worldwide)
Registered trials
3, 0 stopped early
Disease areas
Cancer; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
CACNA1GVoltage-dependent T-type calcium channel subunit alpha-1GO43497
CACNA1HVoltage-dependent T-type calcium channel subunit alpha-1HO95180
CACNA1IVoltage-dependent T-type calcium channel subunit alpha-1IQ9P0X4

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13300
All trials3