Drug

Methsuximide

As of the edition of 20 October 2026, Methsuximide is a small molecule: marketed, first approved in 1963 (CH); acts on CACNA1G, CACNA1H and CACNA1I.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Marketed; latest approval 1982
Kind
Small molecule
Brand name
Celontin
First approved
23 October 1963 (CH)
Approvals on record
3 in 2 regions
Holder of the most recent approval
Pfizer; 2 holders in all
Registered trials
1, 0 stopped early
Disease areas
Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
CACNA1GVoltage-dependent T-type calcium channel subunit alpha-1GO43497
CACNA1HVoltage-dependent T-type calcium channel subunit alpha-1HO95180
CACNA1IVoltage-dependent T-type calcium channel subunit alpha-1IQ9P0X4

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1100
All trials1

Who has held its approvals

CompanyRoleYears
PfizerApplicant and Later holder1963 to now