Drug

AZD-1236

As of the edition of 20 October 2026, AZD-1236 is a small molecule: went quiet in 2018; acts on MMP12 and MMP9.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2018
Kind
Small molecule
Registered trials
6, 2 stopped early
Disease areas
Lungs and airways; Cancer; Digestive system; Inherited and neonatal

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of AZD-1236.

Targets

GeneProteinUniProt
MMP9Matrix metalloproteinase-9P14780
MMP12Macrophage metalloelastaseP39900

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13201
Phase 23201
All trials6

Who ran its trials

CompanyRoleYears
AstraZenecaLead sponsor of trials2008 to now