Drug

Rebimastat

As of the edition of 20 October 2026, Rebimastat is a small molecule: stopped in 2010; acts on MMP1, MMP13 and MMP14 and 3 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2010
Kind
Small molecule
Registered trials
5, 1 stopped early
Disease areas
Cancer; Urinary and reproductive; Infections; Lungs and airways; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

6 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

6 company-target rows are on route A because of Rebimastat.

Targets

GeneProteinUniProt
MMP1Interstitial collagenaseP03956
MMP272 kDa type IV collagenaseP08253
MMP9Matrix metalloproteinase-9P14780
MMP8Neutrophil collagenaseP22894
MMP13Collagenase 3P45452
MMP14Matrix metalloproteinase-14P50281

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 24301
Phase 31100
All trials5

Who ran its trials

CompanyRoleYears
Bristol Myers SquibbLead sponsor of trials