Cisapride
As of the edition of 20 October 2026, Cisapride is a small molecule: withdrawn from the market in 2000; acts on HTR4; no US protection is listed.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Withdrawn from market, 2000
- Kind
- Small molecule
- Brand name
- Propulsid
- First approved
- 29 July 1993 (US)
- Approvals on record
- 4 in 1 region
- Holder of the most recent approval
- Johnson & Johnson; 2 holders in all
- Withdrawn from market
- 1 January 2000 (in some regions)
- Registered trials
- 4, 4 stopped early
- Disease areas
- Digestive system; Hormones; Nutrition and metabolism; Pregnancy and women's health; Urinary and reproductive
US protection
No US protection is listed.
The FDA registers list no drug-substance patent or exclusivity that counts for this drug.
This is the US only.
Companies that need a new molecule because of this drug
1 company on route A because of this drug.
Companies on route A for this drug
In the product1 company is on route A because of Cisapride.
See the 1 company on route A for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Target
| Gene | Protein | UniProt |
|---|---|---|
| HTR4 | 5-hydroxytryptamine receptor 4 | Q13639 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 4 | 4 | 0 | 0 | 4 |
| All trials | 4 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| Johnson & Johnson | Originator, Later holder and Lead sponsor of trials | 1993 to now |