Drug

PRX-03140

As of the edition of 20 October 2026, PRX-03140 is a small molecule: went quiet in 2013; acts on HTR4.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2013
Kind
Small molecule
Registered trials
4, 2 stopped early
Disease areas
Mental health; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 companies on route A because of this drug.

Companies on route A for this drug

In the product

2 companies are on route A because of PRX-03140.

Target

GeneProteinUniProt
HTR45-hydroxytryptamine receptor 4Q13639

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1100
Phase 23102
All trials4

Who ran its trials

CompanyRoleYears
Epix PharmaceuticalsLead sponsor of trials2006 to now
Alachua GovernmentLead sponsor of trials2012 to now