Drug

Mosapride

As of the edition of 20 October 2026, Mosapride is a small molecule: in active development; acts on HTR3A, HTR3B and HTR3C and 3 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2025
Kind
Small molecule
Registered trials
17, 2 stopped early
Disease areas
Digestive system; Cancer; Ear, nose and throat; Heart and blood vessels; Hormones; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
HTR3E5-hydroxytryptamine receptor 3EA5X5Y0
HTR3B5-hydroxytryptamine receptor 3BO95264
HTR3A5-hydroxytryptamine receptor 3AP46098
HTR45-hydroxytryptamine receptor 4Q13639
HTR3D5-hydroxytryptamine receptor 3DQ70Z44
HTR3C5-hydroxytryptamine receptor 3CQ8WXA8

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated6211
Phase 13200
Phase 22010
Phase 32101
Phase 44100
All trials17

Who ran its trials

CompanyRoleYears
IlDong PharmaceuticalLead sponsor of trials2013 to now
GSKLead sponsor of trials2014 to now
Shandong New Time PharmaceuticalLead sponsor of trials2024 to now